Education

B.S., Biology, Morehouse College, Atlanta, GA, 2001
Ph.D., Microbiology, University of Alabama at Birmingham, Birmingham, AL, 2007
Postdoctoral Fellow, University of Alabama at Birmingham, Birmingham, AL, 2007-2008
2nd year FIRST Postdoctoral Fellow, 2008-present

Research Statement

My current research focuses on the Streptococcus pneumoniae surface adhesin PcpA.  Previous studies have shown that PcpA has the ability to elicit protective immunity against infection in murine models of sepsis and pneumonia.  However, for this protein to become a viable vaccine antigen it is necessary to determine if PcpA is present in clincially isolated strains responsible for pneumococcal disease.  In addition is is important to know whether patients who have recovered from pneumococcal infection have anti-PcpA antibodies in their serum.  Addressing these two issues will give us more insight into PcpA's potential for use in a new vaccine against Streptococcus pneumoniae.

Publications

Reid, S.D., Hong, W., Dew, K.E., Winn, D.R., Pang, B., Watt, J., Glover, D.T., Hollingshead, S.K., Swords, W.E. (2009) Streptococcus pneumoniae forms surface-attached communities in the middle ear of experimentally infected chinchillas. J Infect Dis. 199(6):786-94.

Glover, D.T., Hollingshead, S.K., Briles, D.E. (2008) Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis. Infect Immun. 76(6):2767-76. SPOTLIGHT: Article of Significant Interest Selected from This Issue by the Editors

Li, J., Glover, D.T., Szalai, A.J., Hollingshead, S.K., Briles, D.E. (2007) PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation. Infect Immun. 75(12):5877-85.

Emory University School of Medicine
Department of Infectious Diseases
VA Medical Center
1670 Clairmont Road, NE
Atlanta, GA 30033
Tel: 404-321-6111 ext 6941
Email: dtglove@emory.edu