Education

B.S., Biology, Emory and Henry College, Emory, VA, 1996
M.S., Microbiology, Georgia State University, Atlanta, GA, 2000
Ph.D., Molecular Genetics and Biochemistry, Georgia State University, Atlanta, GA, 2008
2nd year FIRST Postdoctoral Fellow, 2008 - present

Research Statement

VE-Cadherin is a trans-membrane protein involved in the adhesion of endothelial cells which form the lining of our vascular system.  My current work focuses on the interaction of VE-cadherin with one of it’s intracellular stabilizing proteins, p120.  Our lab has created a p120 null cell line in which I am currently doing functional studies to determine how the loss of p120 affects endothelial function.  I am also working with a Kaposi Sarcoma viral protein, K5, which has been shown to increase the endocytosis of VE-cadherin by it’s function as an E3 ubiquitin ligase.  

Publications

Emory University School of Medicine
Department of Cell Biology
615 Michael Street
Atlanta, GA 30322
Tel: 404.727.1830
Email: drew.kohlhorst@emory.edu